A series of novel arylpiperazines were synthesized and the target compounds evaluated for atypical antipsychotic activity in apomorphine induced climbing behavior (D2 antagonism), 5-HTP induced head twitches (5-HT2A antagonism) and catalepsy studies in albino mice.The physicochemical similarity of the target compounds with respect glass-dildos to s

Eggs are a major animal protein source for humans.Egg formation is a complex process involved in coordinating various tissues and organs, while blood is OPTIONS_HIDDEN_PRODUCT necessary for gonad differentiation and egg formation.In this study, non-targeted metabolomics technology was employed to determine the serum metabolites at the time point of

In order to mitigate the effects of a changing climate, agriculture requires more effective evaluation, selection, and production of crop cultivars in order to accelerate genotype-to-phenotype connections and the selection of beneficial traits.Critically, plant growth and development are highly dependent on sunlight, with light energy providing pla

Varicella-zoster virus (VZV) is a human herpes virus which causes varicella (chicken pox) as a primary infection, and, following a variable period of latency Keyboard/Synth Parts in neurons in the peripheral ganglia, may reactivate to cause herpes zoster (shingles) as well as a variety of neurological syndromes.In this overview we consider some rec

Abstract Smith-Lemli-Opitz Syndrome (SLOS) is a recessive human disease caused by defective cholesterol (CHOL) synthesis at the level of DHCR7 (7-dehydrocholesterol reductase), which normally catalyzes the conversion of 7-dehydrocholesterol (7DHC) to CHOL.Formation and abnormal accumulation of 7DHC and 7DHC-derived OPTIONS_HIDDEN_PRODUCT oxysterols